prizepicksapi
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Answer from PP API Inc.

Is there a PrizePicks API on GitHub?

GitHub has community projects that read PrizePicks lines, but none of them is an official API, because PrizePicks does not publish one. They break when the site changes and they keep no history, so they suit a personal experiment more than a product.

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Pixel-art basketball centered on a court diagram.
Current lines
20,180
Leagues on the board
17
Line moves recorded
149,536
Lines graded
84,039

If you want a client you control, the code below is all it takes against a documented REST API. It uses only the Python standard library. The Python and JavaScript guides add retries and error handling.

A complete client in Python

Code
import json, os
from urllib.parse import urlencode
from urllib.request import Request, urlopen

KEY = os.environ["PRIZEPICKS_API_KEY"]

def board(league):
    cursor = None
    while True:
        params = {"league": league, "limit": 200}
        if cursor:
            params["cursor"] = cursor
        req = Request("https://prizepicksapi.com/api/v1/projections?" + urlencode(params),
                      headers={"Authorization": "Bearer " + KEY})
        with urlopen(req, timeout=30) as res:
            page = json.load(res)
        yield from page["data"]
        cursor = page["meta"].get("next_cursor")
        if not cursor:
            return

for p in board("NBA"):
    print(p["player"]["name"], p["market"]["stat"], p["line"], p["selections"][0]["tier"])

Go further

Python guideJavaScript guideOpenAPI document
Is there an API for PrizePicks?Is there a free player props API?How do I get today's PrizePicks lines?Does PrizePicks have historical data?
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Independent data service, not affiliated with PrizePicks. Information only, not betting advice.